摘要
A naked-eyed chromo-near infrared fluorescent probe for simultaneous detection of Fe2＋ and C1 has been developed, based on photoinduced electron transfer mechanism （PET）. The fluorophore is cyanine （Cy-SO3）, and the Fe2＋ receptor is 4＇-（aminomethylphenyl）-2,2＇,6＇,2＂-terpyridine （Tpy）. The probe responds linearly and rapidly to [Fe2＋] and [C1 ] variations under physiological conditions and exhibits high sensitivity, good photostability, and excellent cell membrane permeability. The real-time imaging of cellular Fe2＋ was achieved successfully in living HL-7702, HepG2, and RAW264.7 cell lines.
A naked-eyed chromo-near infrared fluorescent probe for simultaneous detection of Fe2＋ and C1 has been developed, based on photoinduced electron transfer mechanism （PET）. The fluorophore is cyanine （Cy-SO3）, and the Fe2＋ receptor is 4＇-（aminomethylphenyl）-2,2＇,6＇,2＂-terpyridine （Tpy）. The probe responds linearly and rapidly to [Fe2＋] and [C1 ] variations under physiological conditions and exhibits high sensitivity, good photostability, and excellent cell membrane permeability. The real-time imaging of cellular Fe2＋ was achieved successfully in living HL-7702, HepG2, and RAW264.7 cell lines.
