摘要
In this work, copolymerization of two functional monomers, glycidyl methacrylate （GMA） and N,N-dimethylaminoethyl methacrylate （DMAEMA）, was firstly carried out via reversible addition-fragmentation chain transfer （RAFT） polymerization successfully. The copolymerization kinetics was investigated under the molar ratio of n[GMA＋DMAEMA]o/n[AIBN]o/n[CPDN]o=300/1/3 at 60℃. The copolymerization showed typical ＂living＂ features such as first-order polymerization kinetics, linear increase of molecular weight with monomer conversion and narrow molecular weight distribution. The reactivity ratios of GMA and DMAEMA were calculated by the extended Kelen-Tudos linearization methods. The epoxy group of the copolymer PGMA-co-PDMAEMA remained intact under the conditions of RAFT copolymerization and could easily be post-modified by ethylenedia- mine. Moreover, the modified copolymer could be used as a gene carrier.
In this work, copolymerization of two functional monomers, glycidyl methacrylate （GMA） and N,N-dimethylaminoethyl methacrylate （DMAEMA）, was firstly carried out via reversible addition-fragmentation chain transfer （RAFT） polymerization successfully. The copolymerization kinetics was investigated under the molar ratio of n[GMA＋DMAEMA]o/n[AIBN]o/n[CPDN]o=300/1/3 at 60℃. The copolymerization showed typical ＂living＂ features such as first-order polymerization kinetics, linear increase of molecular weight with monomer conversion and narrow molecular weight distribution. The reactivity ratios of GMA and DMAEMA were calculated by the extended Kelen-Tudos linearization methods. The epoxy group of the copolymer PGMA-co-PDMAEMA remained intact under the conditions of RAFT copolymerization and could easily be post-modified by ethylenedia- mine. Moreover, the modified copolymer could be used as a gene carrier.
