南宁地区2009-2011年淋球菌抗生素耐药性的检测结果分析

The Analysis of Antibiotic Resistance in Nesisseria Gonorrhoeae in Nanning From 2009 to 2011

目的了解淋球菌对5种抗生素的耐药情况,为制定淋病合理有效的治疗方案提供理论依据。方法对2009-2011年广西南宁地区分离的96株淋球菌,在系统鉴定的基础上,根据世界卫生组织(WHO)标准判定其敏感、中度敏感及耐药。结果 96株淋球菌中β-内酰胺酶(+)菌株为28株;质粒介导的高度耐四环素淋球菌TRNG(+)57株。环丙沙星耐药率为98.96%。头孢曲松和大观霉素未发现耐药菌株。结论南宁地区淋球菌耐药以环丙沙星为甚,四环素和青霉素次之。

Objective To study the resistances of Neisseria gonorrhoeae to five antibiotics in Nanning area. In order to provide fundamental basis for gonorrhea reasonable effective treatment programs. Methods Total 96 strains of Neisseria gonorrhoeae from 3 years（2009 -2011 ）were separated to test their antibiotic susceptibilities based on the systemic identification. And then according to the WHO standard to judge its sensitivity, moder- ate sensitivity and resistance. Results The results showed that there were 28 strains of PPNG and 57 strains of TRNG in 96 gonococcal isolates. The percentage of the resistances to ciprofloxacin were 98.96%. No gono- coccal isolates were resistant to ceftriaxone and spectinomycin. Conclusion In Nanning the gonococci were highly resistant to ciprofloxacin, next were to tetracycline and penicillin.