摘要
青年男性,蛋白尿,低白蛋白血症2年,肾功能正常。光镜下见PAS淡染和不嗜银的物质沉积于肾小球系膜区和外周袢,免疫病理肾小球IgG(含IgG1、IgG2、IgG4)及κ、λ轻链阳性,超微结构可见直径20~30nm的纤维丝状物质和电子致密物沉积,最终诊断为纤维性肾小球肾炎。
A 21-year old man presented with proteinuria, hypoalbuminemia and normal renal lunction for two years. Renal biopsy showed weak PAS-positive and non-argyrophilie deposits in mesangial areas and along GBM. Immunofluereseence indicated glomerular positive staining for IgG, C3, κ and λ light chain. Uhrastructral examination indicated fibrils and electron dense deposits in mesangial, subendothelial and subenpithelial regions. The final diagnosis was fibrillary glomerulonephritis.
出处
《肾脏病与透析肾移植杂志》
CAS
CSCD
北大核心
2012年第5期491-495,共5页
Chinese Journal of Nephrology,Dialysis & Transplantation
关键词
纤维性肾小球肾炎
肾活检
电镜
fibrillary glomerulonephritis renal biopsy electron microscopy