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牙龈蛋白酶及其致病作用 被引量:3

Gingipain and its pathogenicity
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摘要 牙龈卟啉单胞菌是引起和加重牙周炎的重要致病菌,其分泌的牙龈蛋白酶是其主要的毒力因子之一。本文就牙龈卟啉单胞菌牙龈蛋白酶以及牙龈蛋白酶对细菌生长和黏附的影响、对组织的破坏作用、对宿主防御机制的作用等研究进展作一综述。 Porphyromonas gingivalis (P.gingivalis) is recognized as the most important pathogen of periodontitis. Gingipain is thought to be one of the most important virulence factors of P.gingivalis. This paper reviews gingipain and its effects on the growth and adhesion of bacteria, tissue destruction and host defence mechanism,
作者 冯琴 张凤秋
出处 《国际口腔医学杂志》 CAS 2012年第6期794-796,共3页 International Journal of Stomatology
基金 北京市自然科学基金资助项目(7093122) 北京市优秀人才培养计划专项基金资助项目(2009D003012000001)
关键词 牙龈卟啉单胞菌 牙龈蛋白酶 致病 作用 Porphyromonas gingivalis gingipain pathogenicity effect
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