湖州市2007～2010年子宫颈活检结果分析

Analysis on the results of cervical biopsy in Huzhou city from 2007 to 2010

目的:探讨湖州市2007～2010年子宫颈疾病的发病待点,为湖州市子宫颈癌的防治提供基础。方法:回顾性分析湖州市妇幼保健院15 713例阴道镜检查的子宫颈活检病理结果,分析湖州市子宫颈癌和癌前病变的发病特点以及各个不同年龄段的发病情况。结果:15 713例患者中,慢性子宫颈炎10 439例,占66.44%;低级别鳞状上皮内病变(LSIL)4 380例,占27.88%;高级别鳞状上皮内病变(HSIL)703例,占4.47%;鳞状细胞癌164例,占1.04%;腺体异型增生12例,占0.08%;腺癌12例,占0.08%。鳞状细胞癌及腺癌在≥60岁年龄组检出率最高,分别为9.47%及0.97%。在各个年龄段中,随着年龄的升高,LSIL的检出率下降,而鳞状细胞癌的检出率则上升(P<0.01)。结论:湖州市子宫颈癌的前驱病变检出率高,认真定期做好早期筛查,积极处理LSIL和HSIL,有利于湖州市子宫颈癌的预防与治疗。

Objective：To explore the clinical characteristics of cervical diseases in Huzhou city from 2007 to 2010,and provide a basis for preventing and treating cervical cancer in Huzhou city. Methods：The pathological results of cervical biopsy after colposcopy in 15 713 patients from the hospital were analyzed retrospectively,the clinical characteristics of cervical cancer and cervical precancerous lesion and the prevalences in different age groups in Huzhou city were analyzed. Results：Among 15 713 patients,10 439 patients were found with chronic cervicitis,accounting for 66.44%;4 380 patients were found with low-grade squamous intraepithelial lesion（LSIL）,accounting for 27.88%;703 patients were found with high-grade squamous intraepithelial lesion（HSIL）,accounting for 4.47%;164 patients were found with cervical squamous cell carcinoma（SCC）,accounting for 1.04%;12 patients were found with glandular atypical hyperplasia,accounting for 0.08%;12 patients were found with adenocarcinoma,accounting for 0.08%.The detection rates of cervical SCC and adenocarcinoma in ≥60-year-old group were the highest,which were 9.47% and 0.97%,respectively.Among the patients in different age groups,the detection rates of LSIL decreased with age,while the detection rates of cervical SCC increased with age（P〈0.01）. Conclusion：The detection rates of precancerous lesions of cervical cancer was high in Huzhou city,early screening seriously and regularly,treating LSIL and HSIL actively are conducive to the prevention and treatment of cervical cancer in Huzhou city.