中国糖尿病经济负担研究系统综述

Cost-of-illness studies of diabetes mellitus in China： A systematic review

目的探索我国糖尿病经济负担及治疗费用研究的现状及方法。方法对近年来相关中、英文数据库中关于糖尿病治疗费用和经济负担的文献进行系统综述。结果系统检索后共检索到374篇文献，进一步筛选得到40篇符合文献人选和排除标准的文献。文献主要包括经济负担研究和住院费用分析两大类型，所采用的主要研究方法有疾病成本法、推算法和配比对照法，不同方法所产生的研究结果有较大差异。结论不同的研究方法是造成疾病负担研究结果产生差异的最主要原因，使用相同的方法时采用不同的数据来源、调查地点等同样会影响疾病负担研究和费用分析结果。因此公众及政策决策者参考结果时，必须关注疾病经济负担结果背后的研究方法。

Objective To undertake a systematic review of the economic burden of diabetes in China. Methods Published literatures about the medical cost and economic burden of diabetes in China were searched for analyzing the methodologies and results. Results Altogether 374 articles were identified in the literatures. Review of the articles resulted in the identification of 40 of these that met all criteria. Cost of illness studies and hospitalization expenditure per admission comprised the largest source of the studies. Cost of illness approach, calculations from the national survey＇s data and the matching method were adopted in most researches and led to variations of result. Conclusions Differences in research methods are the key determinants of variations of the result. Even the same method with different data sources, patient types or investigating spots still contributes to great variations. Without well-accepted standards to guide researchers in their execution of these studies, policymakers and the general public must be wary of the methods and data source used in their calculation and subsequent results.