用药物经济学方法评价我院抗菌药物治疗痛风是否合理

Feasibility Evaluation of Antibiotics in the Treatment of Gout by Pharmacoeconomics Method

目的:评价我院抗菌药物治疗痛风是否合理。方法:采用药物经济学方法,对使用抗菌药物(青霉素、哌拉西林钠/舒巴坦钠、克林霉素)及不使用抗菌药物治疗痛风的方案进行比较分析。结果:4种治疗方案有效率差异有统计学意义(P<0.01),不使用抗菌药物组有更好的疗效;不使用抗菌药物组与其他3组进行成本比较,差异均有统计学意义(P<0.01或P<0.05),不使用抗菌药物组成本最低。结论:从"医保"付费方角度来看,我院使用抗菌药物治疗痛风不合理。不使用抗菌药物治疗痛风为优势方案。

OBJECTIVE： To evaluate whether it is reasonable to treat gout with antibiotics in our hospital. METHODS： Thera- peutic schemes for gout by using antibiotics （penicillin, piperacillin sodium/sulbactam sodium, clindamycin） and without using anti- biotics were analyzed comparatively. RESULTS： There was statistical significance in the difference of effective rate among 4 thera- peutic schemes （P〈0.01）, and therapeutic efficacy of non-antibiotic treatment group obtained better therapeutic efficacy; there was statistical significance in the difference of cost between non-antibiotic treatment group and other 3 groups （P〈0.01 or P〈0.05）, and the cost of non-antibiotic treatment group was the lowest. CONCLUSION： It is unreasonable to use antibiotics to treat gout in our hospital with a medical insurance perspective. The optimal scheme is that antibiotics are not used for gout.