疏血通注射液治疗急性进展性脑梗死的疗效观察

Study of Shuxuetong Injection on Progressive Cerebral Infarction

目的观察疏血通注射液治疗急性进展性脑梗死的疗效及安全性。方法将100例急性进展性脑梗死患者随机分为治疗组和对照组,各50例。治疗组静脉滴注疏血通注射液;对照组静脉滴注复方丹参注射液,两组其他治疗方式相同。两组治疗前后均进行神经功能缺损程度评分(CSS)及凝血指标测定。结果治疗组的总有效率为88.0%,显著高于对照组的62.0%,差异有统计学意义(P<0.05)。两组患者治疗后3d、7d、14d时CSS评分比较,差异均有统计学意义(P<0.05)。治疗前后两组的血纤维蛋白原、血小板数、凝血时间、凝血酶原时间比较,差异均无统计学意义(P>0.05)。结论疏血通注射液治疗急性进展性脑梗死安全有效。

Objective It is to observe the curative effects safety of shuxuetong injection on progressive cerebral infarction.Methods 100 cases of acute progressive cerebral infarction were randomly divided into treatment group and control group,50 cases in each.The treatment group was given shuxuetong injection by intravenous drip,the control group was given compound danshen injection by intravenous drip,other treatment was the same.Two groups were examined before and after treatment in the degree of neural function defect score（CSS） and coagulation test.Results The total effective rate in treatment group was 88% higher than that of the control group（62%）,the difference was statistically significant（P〉0.05）.Two groups of patients after treatment with 3d,7d,14d CSS score comparison,the differences were statistically significant（P〉0.05）.In two groups before and after treatment of plasma fibrinogen,platelet count,clotting time,prothrombin time,there were no significant differences between them（P〉0.05）.Conclusion Shuxuetong on progressive cerebral infarction is effective and safe.