乌头碱中毒92例临床分析

Clinical analysis of 92 patients with acute aconites poisoning

目的:探讨急性乌头碱中毒患者的临床特征及抢救办法。方法:分析92例急性乌头碱中毒患者的临床资料。结果:入院后经洗胃、导泻,在心电监护下,78例早期应用抗胆碱药物(84.7%)治疗,其中23例应用阿托品(25.0%),55例应用盐酸戊乙奎醚(59.8%);有2例发生室颤并阿斯氏发作,8例发生休克,分别在给予直流非同步电除颤及抗休克治疗后得到恢复。92例患者全部治愈出院,治愈率为100%。结论:乌头碱中毒救治要点是早期诊断,早期及时使用抗胆碱能药物如阿托品、盐酸戊乙奎醚,如出现快速心律失常,使用利多卡因等可提高抢救成功率。

Objective： To explore clinical characteristics and emergency treatment of patients with acute aconites poi- soning. Methods： Clinical data of 92 patients with acute aconites poisoning were analyzed. Results： After gastric lav- age, catharsis, a total of 78 cases （84.7%） received anticholinergic drugs under electrocardiography monitoring in early period, among which there were 23 cases （25 % ） receiving atropine and 55 eases （59.8%） receiving penehycli- dine hydrochloride. There were two patients occurring Adam-stoke attack and they received DC asynchronous elec- tric defibrillation; a total of eight shock patients were given anti-shock therapy routinely, they all got recovery. All 92 patients （100%） were cured and discharged from the hospital. Conclusion： The key point of emergency treat- ment of acute aconites poisoning is its diagnosis in early stage, early use of anticholinergic drugs, such as atropine and penehyclidine hydrochloride, if tachyarrhythmia occurs, lidocaine can increase emergency success rate.