成膜基质对氟化物涂膜抑制釉质早期龋的效果

Effects of the film-forming materials on the prevention of enamel early caries by fluoride varnishes in vitro

目的:比较含不同成膜基质的氟化物涂膜抑制釉质早期龋的效果。方法:将制备的90个釉质试样块随机分成6组,分别应用以5种成膜基质(珂巴树脂、渗透型丙烯酸树脂、甲基丙烯酸乙酯共聚树脂、聚合松香、聚乙烯醇缩丁醛)配制的氟涂膜材料和Duraphat氟涂膜进行处理。采用荧光显微镜和显微硬度计测定各组釉质试样块在pH循环前后的荧光值和硬度值的变化;并通过偏光显微镜观察其脱矿深度。结果:pH循环后各组釉质试样块的荧光值和硬度值均较pH循环前明显降低,其中渗透型丙烯酸组与其他组相比,荧光损失率和硬度值变化率最小,与其他各组相比差异均有统计学意义(P<0.05);偏光显微镜观察显示:各组釉质表面均无实质性缺损,渗透型丙烯酸组釉质脱矿深度最浅。结论:氟化物涂膜具有明显的抑制釉质脱矿的作用,含渗透型丙烯酸树脂的氟涂膜效果最好。

AIM： To evaluate the effects of film-forming materials on the prevention of the enamel early caries by fluoride varnishes in vitro. METHODS ： Ninety bovine enamel blocks were divided into 6 groups and the labial surface of each block was treated with a fluoride varnish containing one of the following film-forming materials ： copal resin （ Copal）, osmotic acrylic resin （ OAR ）, ethyl methaerylate copolymer resins （ PMME ）, polymerized rosin （ Rosin） , polyvinyl butyral（PB） , or a commercially available fluoride varnish, Duraphat, respectively. After removal of the varnish, all enamel blocks were subjected to pH cycling for 7 days, then the percent loss of surface fluorescence and surface hardness and the demineralization depth of each enamel block were tested. RESULTS：All fluoride varnishes significantly reduced the percent loss of surface fluorescence and surface hardness of the enamel blocks, and fluoride varnish containing OAR presented the least percent loss of surface fluorescence and surface hardness and the least demineralization depth, followed by Copal, Duraphat and PB. PMME and Rosin presented the most percent loss of surface fluorescence and surface hardness and the most demineralization depth. CONCLUSION： The film-forming materials of fluoride varnish affect its ability to prevent enamel early caries in vitro significantly and osmotic acrylic resin is a promising film-forming material for fluoride varnish.