溴代稠环芳烃的氧化溴化法合成

Synthesis of Polycyclic Aromatic Hydrocarbons by Oxybromination

以HBr/H2O2为溴化体系,采用氧化溴化法合成了6种稠环芳烃的溴化物。合成反应无需催化剂,通过控制反应温度和溴化试剂用量,可以在稠环芳烃化合物的活性位选择性地单溴化或双溴化,产率可达51.1%～94.2%。产品经熔点和1H NMR法确认,合成操作简单安全,环境污染少,有工业应用前景。

A simple and efficient method has been developed for the oxybromination of six kinds of polycyclic aromatic hydrocarbons with the use of aqueous hydrobromic acid and hydrogen peroxide.The method requires no catalysts,and achieves bromination via the in situ generated active bromine.By controling the reaction temperature and the amount of bromination agent,the reaction can obtain the monobromination or dibromination of polycyclic aromatic hydrocarbons with a yield of 51.1%~94.2%.The oxybromination method is simple,safe,environmental friendly,and suitable for industrial production.The obtained products have been characterized by melting point measurement and 1H NMR.