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阻塞性睡眠呼吸暂停低通气综合征患者血清γ-谷氨酰转移酶水平变化对其并发冠心病的预测作用 被引量：3

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摘要 目的:探讨阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者血清γ-谷氨酰转移酶(GGT)水平的变化及其在OSAHS患者并发冠心病(CHD)中的预测作用。方法:选择正常对照组24例、OSAHS患者45例、0SAHS并CHD患者45例,检测比较3组间血清GGT水平的变化及其与睡眠呼吸指标间的相关性。结果:正常对照组、OSAHS组及OSAHS并CHD组血清GGT水平依次升高,两两间比较差异有统计学意义(P<0.01);0SAHS组及OSAHS并CHD组患者血清GGT水平与AHI、呼吸障碍事件总时间百分比正相关(P<0.05),与最低SaO2及平均最低SaO2负相关(P<0.05)。结论:与正常对照组比较,OSAHS患者血清GGT水平升高,而OSAHS并CHD患者血清GGT升高更加显著,其升高幅度与OSAHS严重程度密切相关,可作为OSAHS患者并发CHD的预测指标。
作者 杨运凤
机构地区 湖州市中心医院心血管内科
出处 《实用医学杂志》 CAS 北大核心 2012年第20期3413-3416,共4页 The Journal of Practical Medicine
关键词 睡眠呼吸暂停 阻塞性 冠心病 Γ-谷氨酰转移酶
分类号 R766 [医药卫生—耳鼻咽喉科]
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参考文献15

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共引文献16

同被引文献26

  • 1王轶娜,杨宇,罗荧荃,卿之驹.经鼻持续气道正压通气对阻塞性睡眠呼吸暂停低通气综合征患者血清C反应蛋白的影响[J].中华结核和呼吸杂志,2004,27(10):695-696. 被引量：15
  • 2陈公平,丁海波,林其昌,黄鸿波,唐爱忠.阻塞性睡眠呼吸暂停低通气综合征患者血清白介素-6的变化[J].国际呼吸杂志,2006,26(6):412-414. 被引量：10
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实用医学杂志
2012年 第20期

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