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Galectin-3在甲状腺癌诊断中的应用价值 被引量：3

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摘要 甲状腺结节性疾病非常普遍,其中绝大多数是良性结节,5%的甲状腺肿块为甲状腺癌。细针穿刺细胞学活检（FNAB）是初步诊断甲状腺良恶性结节最关键的一项检查。但是,大量的案例证明,甲状腺结节的良恶性诊断仍然是临床病理诊断中不可忽视的难题。高达15%的甲状腺癌病例最终不能通过FNAB诊断出来。
作者 陈帅 任建强
机构地区 南昌大学医学院研究生院 上海市第一人民医院宝山分院
出处 《实用医学杂志》 CAS 北大核心 2012年第20期3476-3478,共3页 The Journal of Practical Medicine
关键词 GALECTIN-3 初步诊断 甲状腺癌 甲状腺结节性疾病 甲状腺良恶性结节 细针穿刺细胞学 价值 应用
分类号 R736.1 [医药卫生—肿瘤]
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参考文献19

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同被引文献27

  • 1Di CF, Cope L, Li H, et al. Methylation of the elaudin 1 promoter is associated with loss of expression in estrogen receptor positive breast cancer [J]. PLoS One,2013,8(7) : 628- 630.
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  • 4Macdonald BT, Tamai K, He X. Wnt/β- eatenin signaling: components, mechanisms, and diseases [J]. Developmental cell,2009,17(1) : 9-26.
  • 5All AM, Provenzano E, Bartlett J, et al. Prognosis of early breast cancer by immunohistoebemistry defined intrinsic sub -types in patients treated with adjuvant chemotherapy in the NEAT/BR9601 trial [J]. International Journal of Cancer, 2013,54(12) :133-136.
  • 6Prasad NB, Kowalski J, Tsai H-L, et al. Three-gene mo- lecular diagnostic model for thyroid cancer [J]. Thyroid, 2012,22(3) : 275-284.
  • 7Tzelepi VN, Tsamandas AC, Vlotinou HD, et al. Tight junctions in thyroid carcinogenesis: diverse expression of claudin- 1, elaudin- 4, claudin- 7 and occludin in thyroid neoplasms [J]. Modern pathology,2007,21(1):22-30.
  • 8Resnick MB, Konkin T, Routhier J, et al. Claudin- 1 is a strong prognostic indicator in stage II colonic cancer: a tissue microarray study [J]. Modern pathology, 2004, 18 (4) : 511 -518.
  • 9Fritzsche FR, Oelrich B, Johannsen M, et al. Claudin 1 protein expression is a prognostic marker of patient survival in renal cell carcinomas [J]. Clinical cancer research,2008,14 (21) : 7035-7042.
  • 10Kobawala TP, Patel GH, Gajjar DR, et al. Clinical utility of serum interleukin-8 and interferon-alpha in thyroid disease [J]. J Thyroid Res, 2011,2011 : 270149.

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实用医学杂志
2012年 第20期

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