广西壮族自治区农村居民精神分裂症患病率及影响因素分析

Prevalence of Schizophrenia and its Influencing Factors in Rural Residents in Guangxi Zhuang Autonomous Region,China

目的了解广西壮族自治区农村地区≥15岁居民精神分裂症患病率的分布特征和影响因素,为保护当地居民身体健康提供科学依据。方法 2007年7-12月,采用多阶段分层整群抽样方法随机抽取10个县13 910名≥15岁的农村居民为调查对象进行入户调查。以中国疾病预防控制中心提供的中文版本的复合性国际诊断问卷（CIDI3.0）为筛查工具,以国际疾病及相关健康问题分类第10版（ICD-10）为诊断标准。结果广西农村≥15岁居民精神分裂症终生患病率为9.20‰。精神分裂症终生患病率在不同年龄之间差异有统计学意义（χ2=21.653,P=0.001）,25~岁组患病率（17.26‰）最高。不同教育水平人群的精神分裂症终生患病率差异有统计学意义（χ2=5.008,P=0.025）,高中及以上文化程度人群的患病率（4.74‰）低于初中及以下人群（10.12‰）。不同婚姻状况的精神分裂症终生患病率差异有统计学意义（χ2=58.770,P〈0.01）,未婚人群患病率（22.56‰）最高。不同性别和不同民族间精神分裂症终生患病率差异均无统计学意义（P〉0.05）。多因素非条件logistic回归分析显示,年龄、教育水平、婚姻状况3个因素进入回归模型,是影响广西农村地区精神分裂症患病的主要因素。结论广西农村地区25~34岁、初中及以下文化程度者和未婚人群精神分裂症患病率较高,是广西农村精神分裂症防治的重点人群。

Objective To investigate the prevalence and influencing factors of schizophrenia among people aged more than 15 years in rural in Guangxi Zhuang Autonomous Region.Methods 13 910 subjects aged more than 15 yrs were randomly selected from 10 counties by stratified multi-stage cluster sampling method.All subjects were investigated by face to face interview.The Chinese version of Composite International Diagnostic Interview（CID I3.0） provided by the Chinese Center for Disease Control and Prevention was used as the screening tool and the diagnoses were made with the 10th edition of international classification of Disease Criteria.Results The general lifetime prevalence of Schizophrenia in 11 191 population aged 15 years old or over was 9.20‰.There were significant differences in the general lifetime prevalence between the residents with different age（χ2=21.653,P=0.001）,education（χ2=5.008,P=0.025） and marital status（χ2=58.770,P0.01）.There were no significant differences in the general lifetime prevalence among the residents of different gender and nationality（all P0.05）.By multiple factor no-condition logistic regression analysis,it was found that there were 3 factors including age,education level and marriage status entering thee regression model.Conclusion Factors including age,education level and marriage status are influencing factors of schizophrenia among people aged more than 15 yrs in rural in Guangxi.