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不同浓度舒芬太尼用于剖宫产术后静脉自控镇痛的研究

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摘要 目的探讨剖宫产术后舒芬太尼静脉自控镇痛的最小安全有效浓度。方法将孕36周~40周剖宫产产妇300例分为A、B、C 3组各100例,A组静脉自控镇痛(PCIA)采用1.0μg/mL舒芬太尼+5 mg格拉司琼,B组为1.5μg/mL舒芬太尼+5 mg格拉司琼;C组为2.0μg/mL舒芬太尼+5 mg格拉司琼。观察各组患者术后不同时段疼痛视觉模拟评分(VAS)、镇痛药用量、自控镇痛(PCA)按压次数、恶心呕吐、头晕、呼吸抑制、皮肤瘙痒发生率。结果 A组镇痛镇静效果较B、C 2组差(P<0.05);B、C 2组无明显差异(P>0.05)。恶心呕吐、皮肤瘙痒发生率A与B组低于C组(P<0.05)。结论1.5μg/mL舒芬太尼+5 mg格拉司琼应用于剖宫产术后PCIA的镇痛效果较好,不良反应发生率较低,为安全有效浓度。
作者 汪玉珍
机构地区 灵丘县人民医院
出处 《基层医学论坛》 2012年第29期3822-3823,共2页 The Medical Forum
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