高压氧治疗重型颅脑损伤的临床疗效观察

Observation of Clinical Efficacy of Hyperbaric Oxygen on Severe Traumatic Brain Injury

目的:观察高压氧辅助治疗重型颅脑损伤的临床疗效。方法:68例重型颅脑损伤患者随机分为观察组和对照组各34例,所有患者均根据病情选择手术或保守治疗,观察组在患者病情稳定后加用高压氧辅助治疗,治疗结束后比较两组患者的临床疗效。结果:观察组治疗有效率为91.2%,显著高于对照组的76.5%(P<0.05);治疗后1周和2周观察组的GCS评分均显著高于对照组(P<0.05),治疗后6个月观察组的GOS评分显著高于对照组(P<0.05);治疗后两组患者脑动脉血流速度均较治疗前有明显的改善(P<0.05),且观察的的改善情况优于对照组。结论:选择高压氧辅助治疗重型颅脑损伤的临床疗效好,可改善患者的临床情况和预后,值得临床应用。

Objective： To observe the clinical effect of hyperbaric oxygen（HBO） on severe traumatic brain injury（STBI）.Methods： 68 cases of patients with STBI were randomly divided into observation group and control group,34 cases in each group.All the patients were given surgical or conservative treatment according to pathogenesis.Patients in the observation group were given hyperbaric oxygen therapy when patient＇s condition was stable and ruled out the contraindications.The clinical efficacy of two groups were compared after treatment.Results： The total effective rate of observation group was 91.2%,which was significantly higher than that of control group（76.5%,P0.05）.The GCS score of observation group was markedly higher than that of control group 1 and 2 weeks after treatment（P0.05）;The GOS score of observation group was statistically higher than that of control group six months after treatment（P0.05）.After treatment,the flow velocity of cerebral artery were both significantly improved in two groups（P0.05）,the effect of observation group was much better than the control group.Conclusion： Treatment with hyperbaric oxygen is able to improve the clinical situation and prog-nosis of severe traumatic brain injury,which is worth being generalized.