心理教育对预防精神分裂症复发意义的研究

A comparative study of strengthening insight training to prevent schizophrenia relapse

目的 探讨心理教育对预防精神分裂症复发的作用。方法 对 1995年 8月至 1996年11月 84例首次住院治疗并临床痊愈出院的精神分裂症患者 (实际完成 77例 ,7例脱落 ) ,按出院顺序分为研究组 (4 1例 )和对照组 (36例 ) ,两组均接受同样的药物维持治疗。研究组服氯丙嗪 (15 4± 5 9)mg/d(31例 ) ,氯氮平 (12 8± 44 )mg/d(14例 ) ;对照组服氯丙嗪 (16 7± 48)mg/d(2 7例 ) ,氯氮平 (15 1± 5 1)mg/d(13例 ) ,对研究组进行半年的心理教育 ;于试验前及 1年后 ,分别对两组的复发率、自知力评分和简明精神病评定量表 (BPRS)进行评定和比较。结果 研究组复发率 (7% )低于对照组 (2 5 % ,P <0 0 5 ) ;研究组自知力评分试验后 [(2 6± 0 9)分 ]略低于试验前 [(3 0± 1 1)分 ,P >0 0 5 ],而对照组由(2 8± 1 0 )分升至 (5 2± 2 5 )分 (P <0 0 1) ;研究组BPRS总分及主要因子分均低于对照组 (P <0 0 1)。结论 对缓解期精神分裂症患者进行心理教育 。

Objective The purpose of this study was to explore the effect of psychological education in preventing relapse in schizophrenia patients Methods The subjects of the study was 77 schizophrenia patients who were treated in mental hospital for the first time and had clinically recovered 77 subjects were assigned into two groups by the discharge order Both groups received the same drug treatment, average dosage: study group chlorpromazine(154±59)mg/d (31 case), clozapine(128±44)mg/d(14 case); control group chlorpromazine(167±48)mg/d(27 case), clozapine(151±51)mg/d(13 case), but the psychology education were given to the study group for the first six months, and follow up study was carried out after one year, relapse rate,the insight scales, and the Brief Psychiatric Rating Scale was assessed in both groups Results Relapse rate was lower in the study group(7%) than in control group(25%, P <0 05) In study group, the score of insight was lower after study(2 6±0 9) than before(3 0±1 1, P >0 05), but in control group, the score of insight was higher after study(5 2±2 5)than before(2 8±1 0, P <0 01) The total score of The Brief Psychiatric Rating Scale and main factor were lower in the study group than that in control group( P <0 01) Conclusion Education for recovered schizophrenia might be effective in relieving symptoms and reducing relapse rate