基于AIBN材料的微流体驱动用微型正压源

Micro positive pressure generator based on AIBN for driving micro fluid

针对本课题组早些时候研制的用于微量组织液透皮抽取的微流控芯片,研究了一种基于偶氮双异丁腈(azobi-sisobutyronitrile,AIBN)热分解产生气体的微型正压源,用于为微流控芯片中微量组织液的收集和输运提供驱动力。将AIBN固定到微型加热器上,微型加热器加热AIBN至70℃即可产生一定的正压力。实验结果表明,设计的微型正压源压力可控、易于制造、体积小,8.7mg的AIBN在900mA加热电流下可产生182kPa的压力,满足对微流控芯片中组织液透皮抽取所需的驱动力。

Abstract： In order to provide the driving force for the collection and transport of the micro liquid in a microfluidic chip developed by our research group in earlier research, this paper presents a micro positive pressure generator based on the released gas by thermal decomposition of azobisisobutyronitrile （AIBN）. The AIBN is fixed to a micro-heater and heated to 70 ℃ to produce a certain amount of positive pressure. Experimental measurements show that this micro positive pressure generator can obtain 182 kPa pressure with heating 8.7 mg of AIBN by a heating current of 900 mA. The designed micro positive pressure generator is a smaller size, pressure controllable and easy to produce, and obtained pressure can satisfy the requirements of transdermal interstitial fluid （ISF） extraction.