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神经系统乙脑病毒感染持续时间的探讨

Persistence of Epidemic Encephalitis Virus in the Human Nervous System
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摘要 :目的 :提供人类神经系统中乙脑病毒持续感染的免疫学和病毒学依据。方法 :经临床诊断为乙脑的 2 4 9例患者中 ,经血清和 C.S.F免疫学确诊者 2 18例 ,采用抗 μ链抗体捕获法、反向被动血凝法和小鼠脑内接种法 ,分别对患者 C.S.F中特异性 Ig M、乙脑病毒抗原及乙脑病毒作定期追踪检测。结果 :12 / 2 18( 5.5% )经 C.S.F特异性 Ig M、乙脑病毒抗原和病毒分离 ,符合乙脑病毒持续感染标准。结论 :对传统的乙脑后遗症概念的内涵提出了新的视点。 Objectives:[WT5BZ]The paper provides the evidences of immunology and virology in persistence of epidemic encephalitis B virus (EEBV) in the human nervous system.[WT5HZ]Methods:[WT5BZ]mAb capture method for special IgM.RPHA for the soluble antigen of encephalitis virus B and C.S.F intrabrain vaccination of rats for separation of encephalitis virus B in the different periods of the illness.[WT5HZ]Result:[WT5BZ]12/218 cases (5.5%) are accordence with the standard of the diagnosis of encephalitis sequelae.[WT5HZ]Conclusion:[WT5BZ]TO provide a new conception of the nature of encephalitis B sequelae.[WT5HZ]
出处 《河北医学》 CAS 2000年第9期816-818,共3页 Hebei Medicine
关键词 流行性乙型脑炎 EEB CNS CSF 病毒分离 WT5BZ]Epidemic encephalitis B IgM antibodyviral antigen Virus isolation
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参考文献4

  • 1V-Ravi,Aamajakshi S,Gowda A et al. Laboratory and diagnosis of Japanese encephalitis using monoalonal antibodies and correlation of findings with the outcome[J].Journal of Medical Virology,1989,40:326-329.
  • 2Mathur A,Arora KL,Rawat S et al. Persitence reactivation and latency of Japanese encephalitis virus infection in mice [J]. Journal of Genreral Virology, 1986,67: 381-385.
  • 3George S,Prasad SR,Rao JA et al. Isolation of Japanese encephalitis virus and West Nile virus from fatal cases of encephalitis in Kolar district of Karnataka. [J] Indian Journal of Medical Research,86:131-134,1987.
  • 4杜平等.现代临床病毒[M].北京:人民军医出版社,1991.35,497.

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