摘要
目的探讨口服抗血栓药相关脑出血(OAT-ICH)患者的临床特点。方法回顾性分析该院2009年6月至2011年6月收治的22例OAT-ICH患者的临床资料。结果患者预后和死亡率与发病年龄、格拉斯哥昏迷(GCS)评分、出血量、国际标准化比值(INR)、血肿是否扩大关系密切。结论 OAT-ICH具有出血量大,血肿扩大的持续时间长、发生率高、预后更差,凝血功能异常,GCS评分低等特点;防止血肿进一步扩大对改善预后、降低死亡率非常重要;手术治疗是口服OAT-ICH最主要方式,但手术风险大,围术期管理特别关键。
Objective To explore the clinical characteristics of oral antithrombotic therapy related intracerebral hemorrhage（OAT-ICH）.Methods The clinic data of 22 cases of OAT-ICH was retrospectively reviewed.Results The prognosis and mortality is related to the age,Glasgow Coma Scale（GCS）score,volume of the hematoma,International Normalized Ratio（INR） and hematoma expansion.Conclusion OAT-ICH has clinical characteristics of large hemotoma volume,common and long time frame for hematoma expansion,worse prognosis if hematoma expansion happens,coagulation defects,low GCS score and so on;To improve the prognosis and lower the mortality,we should focus on preventing the hematoma expansion.Surgical therapy is the main treatment to OAT-ICH even if it has a high risk,more attention should be paid to the perioperative management.
出处
《重庆医学》
CAS
CSCD
北大核心
2012年第30期3152-3154,共3页
Chongqing medicine
关键词
纤维蛋白溶解药
脑出血
临床特征
手术治疗
fibrinolytic agents
cerebral hemorrhage
clinical characteristics
surgical therapy
