糖尿病并发败血症患者54例的临床分析

A clinical analysis of 54 diabetes patients complicated with sepsis

目的探讨糖尿病合并败血症患者的临床特征。方法回顾性分析我院54例糖尿病合并败血症患者的原发感染部位、病原学分布,比较G^+与G^-败血症患者间临床特征的差异。结果糖尿病合并败血症的原发感染灶以泌尿道最为常见;致病菌主要为大肠埃希氏菌和肺炎克雷伯杆菌,其次为金黄色葡萄球菌,致病菌的分布存在性别差异;G^+与G^-组败血症组寒战的发生率分别为73.5%和45%,感染性休克发生率分别为32.4%和5%,两组间均有统计学差异(P<0.05)。G^+与G^-败血症血源性播散的发生率分别为30%和32.4%,两组间比较无统计学差异。结论糖尿病合并败血症的致病菌以G^-菌多见,G^+与G^-败血症的临床表现各有异同。

Objective To explore the clinical characteristics of sepsis in patients with diabetes.Methods The primary infection site and pathogen distribution in 54 diabetes patients complicated with sepsis were retrospectively analyzed in our hospital,and the difference of clinical characteristics between G~＋ sepsis and G^-sepsis patients was compared.Results In 54 patients,the most common infection site was urinary tract.The main pathogens were Escherichia coli and Klebsiella pneumoniae,followed by Staphylococcus aureus,and there was statistical difference in the distribution of pathogens between male and female.The incidences of chills and septic shock were significantly higher in G^-sepsis patients than those in G~＋ sepsis patients（73.5%vs 45.0%,32.4%vs 5.0%,P0.05）.The incidences of hematogenous dissemination did not differ between two groups（30%vs 32.4%,P0.05）.Conclusion For diabetes patients complicated with sepsis,the predominant pathogens is G^-bacteria,and there are similarities and difference between G~＋ sepsis and G^-sepsis.