骨髓活检在骨髓涂片增生不良时的临床应用

Clinical value of bone marrow biopsy for dysplasia diagnosed by bone marrow smears

目的探讨骨髓活体组织检查(bone marrow biopsy,BMB)在骨髓液涂片增生不良时的应用价值。方法对455例骨髓检查患者的骨髓活检及涂片进行回顾性分析。结果 455例骨髓检查患者中骨髓涂片增生不良占10.33%(47/455),骨髓活检和涂片联检时表现增生不良的占6.57%(30/455);单一涂片法与骨髓活检和涂片联检法对骨髓增生不良检出率比较,差异有统计学意义(x^2=4.101,P<0.05)。结论骨髓活检与骨髓涂片同时进行联检具有重要意义,可及时避免漏诊与误诊。

Objective To explore clinical value of bone marrow biopsy in the diagnosis of dysplasia diagnosed by bone marrow smears. Methods The results of bone marrow biopsy and smear in 455 cases of our hospital were analyzed retrospectively.Results In 455 cases,the detection rate for dysplasia was 10.33%（47/455）by bone marrow smear,and 6.57%（30/455）by combined detection of bone marrow biopsy and smear,and the detection rate was statistically different（x^2=4.101,P0.05）.Conclusion Combined detection of bone marrow biopsy and smear is significantly important to avoid the missed diagnosis and the misdiagnosis.