摘要
目的优选清半夏炮制工艺。方法采用L9(34)正交试验设计,以浸出物、总有机酸含量为评价指标,对影响清半夏的炮制工艺的因素进行研究。结果优选出清半夏炮制工艺:蒸制温度130℃、时间60min、白矾用量6∶1。结论优选的炮制工艺达到了减毒增效的炮制目的,同《中国药典》2010版方法比较,提高了总酸含量,显著缩短了炮制时间。
Objective To optimize the processing technology of the Pinelliae Rhizoma Praeparatum Cum Alumine（PRPCA）.Methods The water-soluble extractive and the content of organic acids for investigation index,the orthogonal design were used to investigate the influence of the processing technology of the Pinelliae Rhizoma Praeparatum Cum Alumine.Results The optimum process was established as following： the proportion of Pinelliae Rhizoma to Alumen was 6：1,the processing temperature was 130℃ and time 60min.Conclusion The method can reduce toxicity of Pinelliae Rhizoma,in comparison with the china pharmacopoeia,it can obviously reduce processing time and increase the content of organic acids in PRPCA.
出处
《湖北中医药大学学报》
2012年第5期39-41,共3页
Journal of Hubei University of Chinese Medicine
关键词
清半夏
正交设计
炮制工艺
Pinelliae Rhizoma Praeparatum Cum Alumine
Orthogonal design
Processing technology
