无纹紫背苔化学成分的研究

CHEMICAL STUDIES ON THE CONSTITUENTS OF PLAGIOCHASM INTERMEDIUM L.

目的 研究苔纲植物无纹紫背苔 (PlagiochasmintermediumL .)的化学成分。方法 用 95 %的EtOH回流提取 ,所得浸膏分部萃取后经硅胶柱及SephadexLH 2 0柱色谱反复分离纯化 ,并用 1DNMR ,2DNMR及X ray单晶衍射等技术对化合物的结构进行鉴定。结果 从无纹紫背苔中分离到 6个化合物 ,分别鉴定为 :双联苄类化合物Pakyonol(I) ,2 4 乙基胆甾 5 ,2 2 二烯 3β 软脂酸脂 (2 4 ethylcholesta 5 ,2 2 dien 3β ol palmiticacidester ,II) ,2 2 羟基何伯烷 (2 2 hopanol,III) ,β 谷甾醇 (β sitosterol,IV) ,胡萝卜苷 (daucosterol,V) ,甘露醇 (mannitol,VI)。结论 II为新化合物 ,其余化合物为首次从该属植物中分离得到。

AIM To study the chemical constituents of Plagiochasm intermedium L. METHODS The plants were extracted with 95% EtOH and then separated by repeated silica gel and Sephadex LH-20 chromatographies. The structures of compounds isolated were identified by measurement of 1DNMR, 2DNMR spectrometry and X-ray crystallographic analysis. RESULTS Six compounds were isolated. They were elucidated as pakyonol (I), 24-ethylcholesta-5,22-dien-3β-ol palmitic acid ester (II), 22-hopanol (III), β-sitosterol (IV), daucosterol (V), and mannitol (VI). CONCLUSION Compound II is a new compound.