胆总管结石行治疗性ERCP前后CA19—9水平变化的临床观察

Treatment of Common bile Duct Calculi ERCP CA19-9 Level before and after Changes in the ClinicalObservation

目的观察胆总管结石患者行治疗性ERCP前后CA19-9水平变化的特征，并对影响CA19~9变化的相美因素进行分析。方法对我科近年收治的胆总管结石患者106例行治疗性ERCP前后进行CA19-9水半检测。并同步观察患者总胆红素、直接胆红素、转氨酶等指标与血清CA19-9变化的相关性。结果治疗性ERCP前CA19-9升高者37例。行治疗性ER．CP后CA19-9基本恢复正常，CA19-9升高者与其总胆红素、直接胆红素及转氨酶等有明显相关性。结论胆总管结石患者CA19-9升高与结石阻塞胆道有美．作为肿瘤标志物．血清CA19-9对于胆总管结石无特异性，但可以将其作为胆总管结石诊疗过程中观察随访的指标。

Objective To observe the treatment of common bile duct stones ill patients with ERCP CA19-9 level before and after changes in the characteristics, and the effects of CA19-9 changes an attalysis of revant factors. Methods in Our department in recent years were common bile duct stones in patients with ERCP before find after treatmetii in 106 eases of CA199 level detection, and synchronous observation in patients with total bilirubin, direct bilirubiri, transaminase and serum CA19-9 change correlation ~ndex. Results in the treatment of former ERCP CA19-9 increased in 37 cases, the treatment of ERCP CA19-9 CA19-9 returned to normal~ elevated total bilirubin, direct bilirubin and transaminase has obvious relationship and. Conclusion common bile duct stones in patients with elewtted CA19-9 and gallstone obstruction of the biliary tract, as a tumor marker, serum CA19-9 for commori bile duct stones are nonspecific, but can be as common bile duct stones during the diagnosis and treatment follow-up index.