摘要
目的探讨原发性食管小细胞癌（PESC）的临床特点、治疗方法及预后因素。方法回顾性分析55例PESC患者的临床资料，采用SPSS17．0统计软件处理数据，Kaplan-Meier法进行生存分析，Log-rank法进行生存率的比较。结果55例患者的中位生存期为12个月，6、12、24和36个月生存率分别为87．3％（48／55）、50．9％（32／55）、12．7％（7／55）、7.3％（4／55）。多因素分析显示临床分期、治疗方法是影响预后的独立因素。结论PESC易早期转移，预后不佳，综合治疗有助于延长患者生存期。
Objective To analyze the clinical characteristics,treatment and prognosis of primary esophageal small cell carcinoma （PESC）. Methods Fifty-five patients with PESC were analyzed retrospectively. The survival rate was calculated by the Kaplan-Meier method and the Log-rank test using SPSS 17.0 software. Results The median survival time of 55 patients was 12 months. The 6, 12, 24, 36 months survival rates of. these patients were 87.3 % （48/55）, 50.9 % （32/55）, 12.7 % （7/55）, 7.3 % （4/55）, respectively. In multivariate analysis, stage and type of treatment were shown to be independent predictive. Conclusion PESC is a malignant tumor with early metastasis and poor prognosis. Combined therapy may improve the survival time of PESC patients.
出处
《肿瘤研究与临床》
CAS
2012年第10期682-684,共3页
Cancer Research and Clinic
关键词
食管肿瘤
癌
小细胞
综合疗法
预后
Esophageal neoplasms
Carcinoma, small cell
Combined modality therapy
Prognosis
