2003-2010年贵州麻疹控制效果评价

Effect of Measles Control in Guizhou Province,2003-2010

目的对贵州省2003-2010年麻疹麻疹监测系统运转状况及麻疹控制效果进行评价。方法运用描述流行病学的方法对贵州省2003-2010年麻疹流行病及实验室监测资料进行分析。结果 2003-2004年开展麻疹疫苗初始强化免疫后,2005年麻疹发病率下降到0.49/10万,2008年反弹到3.11/10万,再次开展麻疹后续强化后,麻疹发病率再次下降到2010年的0.22/10万。从2005年开始,风疹病例占报告疑是麻疹病例的比例逐渐升高。贵州省麻疹病毒流行的型别未发生改变,2004年分离到5株H1基因型麻疹野病毒,2007-2010年分离到20株H1a基因亚型麻疹野病毒。结论加强麻疹疫苗常规免疫接种及成功开展麻疹疫苗强化免疫,麻疹发病率一定会下降到一个较低的水平。

Objective To analyze measles surveillance system from 2003-2010 and provide scientific basis for measles elimination in Guizhou Province.Methods Data of measles epidemic and laboratory surveillance was analyzed by the descriptive epidemiology.Results The incidence of measles in Guizhou Province reduced to 0.49/105 in 2005 with the help of strengthening mandatory immunization.Then the incidence rates rebounded in 2008 following the incidence rate of 3.11/105.After the follow-up SIAs,the incidence again was reduced to 0.22/105 in 2010.Since 2005,the proportion of rubella cases is increasing gradually in the reported suspect measles cases,.The provincial measles lab separated 5 strains H1a genotype wild measles virus in 2004 and 20 strains of the same virus from 2007-2010,which showed that the popular type of measles virus in Guizhou province had not changed.Conclusion The incidence of measles could be reduced to a lower level by strengthening mandatory routine immunization and by successfullt carrying out measles vaccine SIAs.