预防性手术干预对晚期血吸虫病患者生存质量的影响

Influence of preventive surgery intervention on life quality of patients with advanced schistosomiasis

目的探讨预防性贲门周围血管离断术对晚期血吸虫病(晚血)患者生存质量的影响。方法回顾性收集2000 01-2009 12潜江市二医院晚血病人临床资料,分析预防性贲门周围血管离断术对晚血的治疗效果。结果施行预防性贲门周围血管离断术与治疗性断流术患者3年内上消化道再出血率差异有统计学意义(P<0.01),5年以上再出血率差异有统计学意义(P<0.05),腹水与肝昏迷差异无统计学意义(P>0.05),生活自理能力与日常劳动能力差异有统计学意义(P<0.01),生活不能自理与正常劳动两项差异无统计学意义(P>0.05),术后远期死亡率差异有统计学意义(P<0.05)。结论预防性贲门周围血管离断术治疗晚血疗效可靠,可显著改善患者生存质量。

Objective To investigate the influence of preventive pericardial devascularization on the life quality of patients with advanced schistosomiasis. Methods The clinical data of advanced schistosomiasis patients who received the preventive peri-cardial devascularization from January 2000 to December 2009 （140 cases） were collected and analyzed retrospectively, and other 81 cases without preventive perieardial devascnlarization served as controls. Results Compared with that of the control group, the long term upper gastrointestinal rebleeding within 3 years of the study group was much fewer （P 〈 0.01 ）, while that of more tharl 5 years was fewer （P 〈 0.05） ; there were no differences in ascites and hepatic coma between the two groups （P 〉 0.05 ） ; the abilities of daily life and labor of the study group were much better than those of the control group （P 〈 0.01 ）, and those of taking care of themselves and lost ability of labor were not significant between the two groups （P 〉 0.05） ; the long term death rate after surgery of the study group was significantly lower than that of the control group （P 〈 0.05）. Conclusion The effect of preventive pericardial devascularization in the treatment of advanced schistosomiasis is reliable and the life qualities of the patients improve.