胺碘酮治疗充血性心力衰竭临床分析

The clinical analysis use of amiodarone in the treatment of congestive heart failure

目的探讨胺碘酮治疗充血性心力衰竭心律失常的临床疗效与安全性。方法选取80例充血性心力衰竭(CHF)合并室性心律失常患者,随机分为对照组和治疗组,对照组给予常规抗心衰治疗,治疗组在对照组治疗基础上加用胺碘酮治疗,对比分析两组患者在心功能改善、抗心律失常、左室射血分数(LVEF)、心律衰竭再入院率及药物不良反应等反面的情况。结果胺碘酮组在抗心律失常、心功能改善、左室射血分数、心律衰竭再入院率等方面均明显优于对照组,差异有统计学意义(P<0.05)。结论胺碘酮是治疗充血性心力衰竭合并室性心律失常有效的药物,使用安全。

Objective To study of amiodarone in treatment of congestive heart failure arrhythmia of clinical efficacy and safety. Methods 80 patients with CHF complicated with ventricular arrhythmia patients, were randomly divided into control group and treatment group, the control group was given routine anti heart failure treatment, the treatment group was treated with amiodarone therapy, comparative analysis of two groups of patients in improving cardiac function, arrhythmia, left ventricular ejection fraction （ LVEF）, rhythm of the heart failure readmission rates and adverse drug reaction and other negative situation. Results Antiarrhythmic amiodarone group, improvement of heart function, left ventricular ejection fraction, rhythm of the heart failure readmission rates and other aspects were significantly better than the control group, the difference was statisti- cally significant （ P 〈 0.05 ）. Conclusion Amiodarone is the treatment of congestive heart failure and ventrie- ular arrhythmia of effective drugs, safe use. Adverse reaction to light.