济宁市鼠类肺螨病的调查

Survey of pulmonary acariasis in rodents in Jining City

目的调查在木材、面粉加工场所鼠类肺螨的病原并分析其病理特征。方法提取鼠类肺组织总RNA,设计肺螨变应原引物进行分子生物学检测,对阳性鼠的肺组织进行病理检查。结果调查济宁市内木材、面粉加工场所以及社区12处,共捕鼠27只,PCR检测3只发现螨类变应原阳性条带,阳性肺组织经病理验证与肺螨病的典型特征相吻合。结论调查显示肺螨病的流行与特定的环境有关,肺螨变应原方法有利于肺螨病的诊断。

Objective To survey the pathogen and pathological features of pulmonary acariasis in wood processing sites and flour mills.Methods Total RNA was extracted from the rodent lung tissue.Pulmonary acaria allergen primers were designed for molecular biology detection and rodent lung tissue was pathologically tested.Results Three pulmonary acariasis were obtained from 27 rodents.The positive results of pathological verification were in accordance with the typical characteristics of pulmonary acariasis.Conclusion The epidemic of pulmonary acariasis was associated with the environment,and the mite allergen method can be bused for the diagnosis of pulmonary acariasis.