上海市闸北区45岁及以上居民空腹血糖异常情况及其危险因素分析

Condition and Risk Factors of IFG Among Residents Over and Include 45 Years Old in Zhabei District

目的了解上海市闸北区45岁及45岁以上居民空腹血糖异常情况,并分析其危险因素,为前移糖尿病预防工作提供依据。方法采取随机整群抽样方法,按5%比例从闸北区常住人口中抽取16592人,并将该人群分为空腹血糖异常组和非异常组。采用t检验、χ2检验、Fisher精确概率法及Wilcoxon秩和检验对数据进行单因素分析;采用非条件Logistic回归进行多因素分析。结果研究发现,空腹血糖异常者1 524人,占9.2%。单因素分析结果表明,空腹血糖异常组的年龄、户籍人口、文化程度、颈围、体重、体质指数、腰臀比、血压值、空腹血糖、总胆固醇、甘油三酯、低密度脂蛋白、癌胚抗原、肝功能指标、空腹血糖异常史比例和糖耐量异常史比例等均高于非异常组,身高和高密度脂蛋白则低于非异常组。多因素分析结果显示,空腹血糖异常史、糖耐量异常史、腰臀比、高密度脂蛋白、性别、低密度脂蛋白、甘油三酯、体质指数、年龄、收缩压、血清丙氨酸氨基转移酶、血清天门冬氨酸氨基转移酶和谷氨酰基转移酶是空腹血糖异常的危险因素。结论闸北区有一定的空腹血糖异常人群,需要通过定期健康体检和健康管理,从掌握空腹血糖异常、糖耐量异常史及其他相关生理、生化指标异常变化情况,培养健康的行为和生活方式,以及关注老年女性健康等方面入手,早期有效地预防空腹血糖异常和糖尿病。

OBJECTIVE To understand the condition and the risk factors of impaired fasting glucose（IFG）among residents over and include 45 years old in Zhabei District, Shanghai, so as to provide suggestion for moving forward diabetes prevention tasks. METHODS 16 592 residents were selected among permanent residents of Zhabei by randomized cluster sampling method with proportion of 5% and was divided into 2 groups, one of which was normal fasting glucose（FG）group and the other was abnormal FG group. The study used t test, chi-test, fisher＇s exact test and wileoxon rank sum test in univariate analysis and non-conditional logistic regression in multivariate analysis. RESULTS The study showed that people in IFG group had 1 524 persons and accounted for 9.2%. The univariate analysis showed that people in abnormal group were older than normal FG group, and there were more residents with hukou, IFG history and IGT history in abnormal group than those in normal group. Also, the education level and values of neck circumference, weight, BMI, WHR, BP, FG, TG, TC, LDL-C, CEA and liver function of people in abnormal group were higher than those in normal group. Whereas, the value of height and HDL-C was lower in abnormal group than those in normal group. The multivariate analysis showed that factors such as IFG history, IGT history, WHR, HDL-C, sex, LDL-C, TG, BMI, age SBP, ALT, AST, and GGT were the risk factors of abnormal FG. CONCLUSIONS There were quite amount of people with IFG needed to pay attention to. We could effectively prevent people from IFG and diabetes by regular physical examination and health management and through knowing their IFG and IGT history and other important physiological and biochemical indices, helping them to form good living habits, and paying more attention to old female.