制霉菌素联合高流量氧治疗新生儿臀炎临床观察

Clinical Investigation of Topical Oxygen Therapy Combined with Nystatin in Newborn Eczema

目的:探讨制霉菌素联合局部给氧治疗新生儿臀炎的临床疗效。方法:选取2010年2月至2011年1月我院收治的新生儿臀炎56例,采用分层随机抽样法将56例患儿分为实验组和对照组各28例,实验组采取局部氧疗联合制霉菌素治疗,对照组仅采取局部氧疗,比较两组患儿的治愈时间及临床疗效。结果:实验组有效率为92.9%,对照组有效率为71.4%,两组比较差异有统计学意义(P<0.05)。实验组患儿平均治愈时间(4.1±1.3)d,对照组平均(6.5±1.6)d,两组比较差异有统计学意义(P<0.05)。结论:制霉菌素联合局部给氧治疗新生儿臀炎临床疗效显著,能有效缩短治愈时间,值得临床推广应用。

Objective： To investigate the clinical efficacy of topical oxygen therapy combined with nystatin in newborn eczema. Methods： From February of 2010 to January of 2011,56 patients with newborn eczema were selected from Chinese Medicine hospital of Pengshui County and randomly divided into two groups. Each group contained 28 patients. The experimental group was treated with topical oxygen therapy combined with nystatin. The control group was treated with topical oxygen therapy. Both groups were compared for healing time and clinical effects. Results： In the experimental group, the efficiency rate was 92.9% ; in the control group, the efficiency rate was 71.4%. There was a significant difference between the two groups in efficiency （P〈0.05）. Healing time in the experimental group was （4.1 ±1.3 ） days, in the control group it was （6.5 ± 1.6 ） days, there was a significant difference between the two groups in healing time （P〈0.05）. Conclusions： Topical oxygen therapy combined with nystatin treatment in newborn eczema has significant effects and reduces healing time, which is worthy of clinical application.