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磷酸肌酸钠对老年全麻患者术后认知功能的影响 被引量：10

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摘要 目的通过简易智能状态检查法(MMSE)行神经心理学测试,观察磷酸肌酸钠对老年全麻患者术后认知功能的影响。方法选择老年全麻腹部手术患者60例,随机分为试验组即磷酸肌酸钠组(30例)和对照组(30例)。在全麻插管后试验组静点磷酸肌酸钠2 g,对照组静点等容积生理盐水,两组麻醉诱导方法及维持用药相同。于麻醉前和术后3 h、1 d、2 d时分别记录MMSE评分。结果 MMSE评分在两组术后3 h、1 d、2 d时均较术前明显降低(均P<0.05),但实验组评分在术后3 h、1 d、2 d时均明显高于对照组(均P<0.05)。实验组术后3 h、1 d、2 d时术后认知功能障碍(POCD)的发生率较对照组均降低(均P<0.05)。结论老年全麻患者术中应用磷酸肌酸钠能提高术后认知功能,降低POCD的发生率。
作者 高晶 周伟 吕国义
机构地区 天津医科大学附属第二医院 天津中医学院第二附属医院
出处 《中国老年学杂志》 CAS CSCD 北大核心 2012年第20期4407-4408,共2页 Chinese Journal of Gerontology
关键词 磷酸肌酸钠 术后认知功能 术后认知功能障碍
分类号 R614 [医药卫生—麻醉学]
  • 相关文献

参考文献6

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共引文献190

同被引文献88

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引证文献10

二级引证文献45

中国老年学杂志
2012年 第20期

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