D-二聚体检测在新生儿重度溶血病中的应用价值

The Application Value of D-dimer Detection in Newborns' Serious Haemolytic Disease

目的探讨D-二聚体(D-D)在新生儿重度溶血病中的临床意义。方法将我院住院治疗的50例重度溶血病新生儿作为观察组,将同期在我院出生的50例正常足月新生儿作为对照组,检测两组新生儿D-D水平,并比较两组间差异。结果重度溶血病新生儿组存在高凝状态,两组新生儿D-二聚体比较差异有统计学意义(P<0.05)。结论测定血浆D-D对新生儿溶血病高凝状态的早期诊断、及指导治疗有重要意义。

Objective To investigate the clinical significance of D-dimer（D-D） in the newborns＇ serious haemolytic disease.Methods Select 50 cases of the hospitalization of newborns with severe hemolytic disease as observation group,and 50 cases of the normal term newborns in same period as the comparison group,check the D-D level and compare the differences between the two groups.Results Hypercoagulability was existed in the group of newborns with serious hemolytic disease.The difference of D-D level between two groups showed statistical significance（P0.05）.Conclusion The determination of plasma D-D level plays an important role in early diagnosis and timely treatment on the hypercoagulability of newborns＇ hemolytic disease.