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Catalyst free synthesis of fused pyrido[2,3-d]pyrimidines and pyrazolo[3,4-b]pyridines in water 被引量:1

Catalyst free synthesis of fused pyrido[2,3-d]pyrimidines and pyrazolo[3,4-b]pyridines in water
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摘要 A one-pot, three-component condensation reaction of an aldehyde, benzoyl acetonitrile (3-oxo-3-phenylpropane nitrile) and 6- amino-1,3-dimethylpyrimidine-2,4(1H,3H)-dione or 3-methyl-l-phenyl-lH-pyrazol-5-amine in water to give fused pyrido[2,3- d]pyrimidines and pyrazolo[3,4-b]pyridines in high yields without any catalyst, is described. A one-pot, three-component condensation reaction of an aldehyde, benzoyl acetonitrile (3-oxo-3-phenylpropane nitrile) and 6- amino-1,3-dimethylpyrimidine-2,4(1H,3H)-dione or 3-methyl-l-phenyl-lH-pyrazol-5-amine in water to give fused pyrido[2,3- d]pyrimidines and pyrazolo[3,4-b]pyridines in high yields without any catalyst, is described.
出处 《Chinese Chemical Letters》 SCIE CAS CSCD 2012年第10期1149-1152,共4页 中国化学快报(英文版)
基金 the financial support of the Research Council of the University of Isfahan
关键词 AMINOPYRAZOLE Aqueous media 3-Methyl-l-phenyl-lH-pyrazol-5-amine Pyrazolo[3 4-b]pyridine Aminopyrazole Aqueous media 3-Methyl-l-phenyl-lH-pyrazol-5-amine Pyrazolo[3,4-b]pyridine
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