上海心脏健康研究队列中40～70岁女性年龄、绝经年限与心血管病危险因素聚集关系探讨

Relationship of age and years since menopause with clustering of cardiovascular disease risk factors in 40 to 70-year-old females in Shanghai Heart Health Study Cohort

目的:探讨女性年龄、绝经年限与血脂异常、高血压、糖尿病、肥胖等心血管病危险因素聚集之间的关系。方法:利用上海心脏健康研究队列2010年6月至7月所做的4 049名40～70周岁女性居民的心血管病危险因素横断面调查资料,将研究对象分成6个年龄组,分析年龄、绝经年限与危险因素之间的相关性。结果:年龄与心血管病危险因素聚集程度高度正相关(P<0.01),年龄越大,危险因素聚集程度越高;在控制年龄因素后,绝经年限与心血管病危险因素聚集程度高度正相关(P<0.01),绝经年限越长,危险因素聚集程度越高。结论:需加强绝经期前后女性心血管疾病的防控工作,同一年龄阶段妇女中尤其需针对早绝经者加强预防措施。

Objective To study the relationship of women＇s age and years since menopause with clustering of cardiovascular disease risk factors, such as dyslipidemia, hypertension, diabetes and obesity. Methods Data were collected from the cross-sectional survey about cardiovascular disease risk factors in Shanghai Heart Health Study Cohort from June to July in 2010. A total of 4 049 females aged 40-70 participated this survey, and were divided into six groups by age. The relationship of years since menopause with clustering of risk factors was focused on. Results A positive correlation was found between age and clustering of cardiovascular risk factors （P〈0.01）. When the factor of age was controlled, years since menopause and clustering of cardiovascular risk factors was highly positive-correlated （P〈0.01）. Conclusions Strengthening the prevention and control of cardiovascular diseases for premenopausal and postmenopausal women is highly needed, particularly for those who had early menopause in the same age group.