肝硬化食管静脉曲张出血的早期防治
摘要
30%的代偿期肝硬化病人和60%的失代偿期肝硬化病人合并有食管静脉曲张。食管静脉曲张破裂出血起病急,是肝硬化患者主要的致死原因,即使病人渡过了首次出血的危险期,1年内再出血率也高达70%,死亡率为33%。面对这样灾难性的后果,最好的措施是预防首次出血的发生,因此临床上控制肝硬化合并食管静脉曲张患者的首次出血显得尤为重要。
出处
《临床消化病杂志》
2012年第5期312-314,共3页
Chinese Journal of Clinical Gastroenterology
参考文献17
-
1D' AMICO G,DE FRANCHIS R, COOPERATIVEG Study Group. Upper digestive bleeding in cirrhosis. Post-therapeutic outcome and prognostic indicators[J]. Hepatology, 2003, 38:599.
-
2GARCIA-TSAO G, GROSZMANN RJ, FISHER RL, et al. Portal pressure, presence of gastroesophagel varices and variceal bleeding [ J]. Hepatolog, 1985 5:419.
-
3D' AMICO G, PAGLIARO L, BOSCH J. The treatment of portal hy- pertension : a meat- analytic review [ J ]. Hepatology, 1995,22:332.
-
4MERKEL C, MARIN R, ANGELI P, et al. A placebo-controlled clini- cal trial of nadolol in the prophylaxis of growth of small esophageal varices in cirrhosis[ J]. Gastroenterology 2004, 127:476.
-
5MERKEL C, BOLOGNESI M, SACERDOTI D, et al. The hemody- namic response to medical treatment of portal hyertension as a predic- tor of clinical effectiveness in the primary prophylaxis of variceal bleeding in cirrhosis[ J]. Hepatology, 2000,32:930.
-
6TALWALKER JA, KAMATH PS. An evidencq-based medicine ap- proach to beta-blocker therapy In patients with cirrhosis [ J ]. Am J Med,J2004, 116:759.
-
7LAY CS, TSAI YT, TEG CY, et al. Endoscopic varieeal ligation in prophylaxis of first variceal bleeding in cirrhotic patients with high- risk esophageal varices[ J]. Hepatology, 1997,25 : 1346.
-
8IMPERIALE TF, CHALASAN . A meta- analysis of endoscopic variceal ligation for primary prophylaxis of esophageal variceal bleed- ing[ J]. Hepat01og,2001, 33:802.
-
9LUI HF,STANLEY J, FORREST EH, et al. Primary prophylaxis of variceal hemorrhage a randomized controlled trial comparing band ligation, propranolol, and isosorbide mononitrate [ J ]. Gastroenterolo- gy, 2002,123:735.
-
10SARIN SK,WERNER M, AGARWAL SR, et al. Endoscopic variceal ligation plus propranolol versus endoscopic variceal ligation alone in primary prophylaxis of variceal bleeding [ J ]. Am J Gastroenterol, 2005, 100:797.
-
1陈国庆.奥曲肽治疗肝硬化食管静脉曲张出血41例[J].中原医刊,1999,26(7):38-39.
-
2朱向阳.肝硬化食管静脉曲张出血的药物预防[J].临床肝胆病杂志,1994,10(2):68-69. 被引量:4
-
3陈义森,高冀蓉.循证医学与肝病临床实践[J].传染病网络动态,2004(1):33-37.
-
4王现强(综述),朱俊明(审校).主动脉夹层的介入治疗[J].心脑血管病防治,2004,4(6):54-56. 被引量:9
-
5徐文端.年过60岁,每半年查一次血糖[J].家庭医学(上半月),2011(1):16-17.
-
6张华雄.硫酸镁在急性心肌梗死治疗中的应用[J].中国基层医药,2004,11(5):618-618. 被引量:4
-
7帮您渡过饥饿关[J].中国保健营养,2004(11):73-73.
-
8周永安,王化河,李爱清.美能与拉米夫定联合治疗活动性肝硬化30例[J].第四军医大学学报,2004,25(20):1869-1869. 被引量:1
-
9朱云秋,陈士良,郑小荣.急性心肌梗塞患者溶拴后心理因素与预后的关系[J].中国心血管康复医学,1996,5(1):91-92.
-
10张曙明,牛秀峰.奥曲肽与垂体后叶素治疗肝硬化食管静脉曲张出血疗效对比[J].中原医刊,2001,28(4):5-6. 被引量:1