摘要
以3,5-二羟基苯甲酸、硫酸二甲酯为原料合成3,5-二甲氧基苯甲酸中间体,在多聚磷酸催化下与邻苯二胺合成2-(3',5'-二甲氧基苯基)苯并咪唑。主要就中间体和目标物的反应条件进行了探讨,产率可达53.70%。
2-(3′,5′-dimethoxy-phenyl) benzimidazole was synthesized by inermediate 3,5-dimethoxybenzoic acid,which prepared with 3,5-dihydroxybenzoic acid and dimethyl sulfate,polyphosphoric and o-phenylenediamine.Reaction conditions of the intermediate and product were mainly discussed,and the yield was up to 53.70%.
出处
《广州化工》
CAS
2012年第20期65-67,共3页
GuangZhou Chemical Industry