重庆市万州区2010年-2011年流感病毒检测结果分析

Analysis of influenza virus detection results in Wanzhou district of Chongqing from 2010 to 2011

目的:了解流感流行趋势及毒株变化情况,为制定流感防控策略提供科学依据。方法:利用实时荧光PCR法对流感监测标本进行流感病毒核酸检测,阳性标本进行病毒分离。结果:804份标本检出流感病毒核酸阳性168份;分离流感毒株57株。2010年流感高峰期发生在8月,以季甲H3型为优势毒株;2011年流感高峰期出现1月-3月,以新甲H1N1为优势毒株。流感患病率无性别差异,以5～年龄组流感病毒阳性率最高。结论:2010年-2011年万州区流感流行分别以季节性H3N2型、B-victoria系和新甲H1N1型为优势毒株。预防流感流行的重点人群是在校期间的中小学生。

Objective：To understand the epidemic trend of the influenza virus strain in Wanzhou district of Chongqing, to provide evidence for the disease prevention and control. Methods： Throat swabs of influenza - like patient collected from the flu monitoring hospital were detected by real -time RT- PCR and isolated and identified with MDCK cells. Results： There were 168 samples to be positive of 804 samples. 57 strains were isolated from the total samples. The flu peak was found in August with seasonal influenza A （ H3 ） as predominant strain in 2010, while in 2011, the period from January to March was the peak season with the new A（H1N1 ） as predominant strain. There was no significant difference between male and female, 5 - year - old group had the highest positive rate. Conclusion： B - Victoria and seasonal H3N2 were the main pandemic strains in Wanzhou in 2010. The new A （HINI） and B- victoria were the main pandemic strains in Wanzhou in 2011. Prevention of flu itffection outbreak should be focused on primary and middle school students.