卵磷脂络合碘治疗AMD的疗效分析

Research of exudative age-related macular degeneration treated with iodized lecithin tablets

目的:探讨卵磷脂络合碘(沃丽汀)对湿性型老年性黄斑变性(AMD)的治疗效果。方法:将53例60眼确诊为湿性型的AMD患者分成治疗组(26例30眼)及对照组(27例30眼),治疗组用卵磷脂络合碘治疗,对照组用安慰剂治疗,67d后分别进行OCT检查。根据OCT检查结果,评价其疗效。结果:治疗组治愈16眼,好转9眼,无效5眼,总有效率83.3%。对照组治愈2眼,好转8眼,无效20眼,总有效率33.3%。治疗组治疗后视力明显提高,黄斑区视网膜厚度明显减少,两组疗效有显著性差异,治疗组优于对照组。结论:卵磷脂络合碘治疗湿性老年黄斑变性有显著疗效。

AIM：To discuss the clinical application value of the optical coherence tomography（OCT） in the treatment of exudative age-related macular degeneration（AMD） by iodized lecithin tablets.METHODS：Totally 53 cases 60 eyes diagnosed with exudative AMD were divided into two groups：the treatment group（26 cases,30 eyes） treated with iodized lecithin tablets and the control group（27 cases,30 eyes） treated with vitamin E and vitamin C.OCT was used to check all the cases after 67 days.The curative effect was evaluated based on OCT outcome.RESULTS：：In treatment group,16 eyes were cured,9 eyes improved and 5 eyes had no effect after the treatment of iodized lecithin tablets,and the total effective rate was 83.3%.In control group,2 eyes were cured,8 eyes improved and 20 eyes had no effect without the treatment of iodized lecithin tablets,and the total effective rate was 33.3%.The visual acuity of treatment group improved obviously,and the macular retina thickness decreased obviously.The curative effect of two groups had significant difference.The treatment group was superior to the control group.CONCLUSION：Iodized lecithin tablets have significant curative effect in treating exudative AMD.