小牛血去蛋白提取物眼用凝胶治疗LASIK术后干眼症

Effects of protein-free calf blood extract eye gel on dry eye syndrome after laser in situ keratomileusis

目的:观察小牛血去蛋白提取物眼用凝胶预防和治疗LASIK术后患者干眼症的效果。方法:选取LASIK术后患者136例272眼,实验组68例136眼术后滴用小牛血去蛋白提取物眼用凝胶和重组人表皮生长因子滴眼液,每日4次;对照组68例136眼术后不用小牛血去蛋白提取物眼用凝胶,余处理两组相同。术前、术后1,2wk;术后1mo均进行泪液学检查进行比较。结果:术后各时间点实验组的角膜染色比例均小于对照组,术后各时间点Schirmer值和BUT值实验组均优于对照组(P<0.05)。结论:LASIK术后应用小牛血去蛋白提取物眼用凝胶可以促进角膜上皮的修复、改善泪液分泌及维持泪膜的稳定性。

AIM：To observe effects of using protein-free calf blood extract eye gel on dry eye syndrome after laser in situ keratomileusis（LASIK）.METHODS：Totally 136 patients 272 eyes treated with LASIK were divided into two groups according to using protein-free calf blood extract eye gel or not.Tear tests were performed before and after surgery and contrasted between two groups.RESULTS：：Tear tests of protein-free calf blood extract eye gel group were better than that of control group（P0.05）.CONCLUSION：Protein-free calf blood extract eye gel can benefit the epithelium recovery from mechanical injury,and stabilize lacrimal film after LASIK.