摘要
双酚A及双酚类环氧衍生物是一种内分泌干扰物,易从金属罐头涂层迁移到食品内容物中。本文建立了一个高效液相色谱-荧光检测法同时检测罐头模拟物中14种双酚类化合物的分析方法。在10～1000ng/mL质量浓度范围,双酚A和各双酚类环氧衍生物的响应峰面积与其相应浓度呈良好相关性,最低检出限在1.41～3.66ng/mL之间;在10～250ng/mL添加水平范围内,平均回收率在72.55%～102.79%之间,日内和日间相对标准偏差均小于10%。之后将此方法应用于测定食品罐头中该双酚类化合物在不同食品模拟物中的迁移情况。
BPA and its derivatives are endocrine disrupting chemicals （EDCs）, they migrate from the can lacquers into food content. In this paper, a high performance liquid chromatography （HPLC-FLD） method for simultaneous determination of 14 bisphenol A-related compounds from food simulants has been explored. The linear range was 10-1 000 ng/ mL for 14 bisphenol A-related compounds with the good linear relation, and the correlation coefficients was 0.9993~ 0.9999. The limit of detection （LOD） were 1.86-3.44 ng/mL for all analytes respectively, the recoveries of blank samples spiked at three levels were 70.46%-103.44%, and both the inter and intra relative standard deviation（RSD）〈10%. Final- ly, this method was applied in determining of these bisphenol A-related compounds migration level in 5 food simulants.
出处
《中国食品学报》
EI
CAS
CSCD
北大核心
2012年第9期186-191,共6页
Journal of Chinese Institute Of Food Science and Technology
基金
浙江省科技厅项目(2010C32G2050021)
浙江自然科学基金(Y3100689)
