创伤患者输血后发生细菌感染的危险因素探讨

Risk factors for bacterial infection in trauma patients after transfusion of red blood cells or platelets

目的探讨创伤患者在输注红细胞或血小板后发生细菌感染的危险因素。方法对2007年1月至2012年1月在我院输注红细胞或血小板后发生细菌感染的56例创伤患者(感染组)与输血后未发生感染的140例创伤患者(未感染组),采用多元回归方法对感染危险因素进行分析。结果创伤患者输血后感染与输注保存14天以上的红细胞密切相关[OR1.038(95%CI:1.01～1.07),P=0.036],而与输注红细胞的数量或血小板的数量无关。结论输注保存时间超过14天的红细胞是创伤患者输血后感染的一个重要危险因素。

Objective To analyze the risk factors for bacterial infection in trauma patients after transfusion of red blood ceils （RBC） or platelets. Methods A retrospective study was conducted. One hundred and ninety six trauma patients were treated with a RBC or platelet transfusion during the period from January 2007 to January 2012 in our hospital. Risk factors of bacterial infection after blood transfusion were determined by using the multivariable logistic regression. Results There were 56 patients （29%）were suffered from a bacterial infection after blood transfusion. Statistical analysis showed that transfusion of RBC stored for more than 14 days was as- sociated with infection in trauma patients[odds ratio was 1. 038（95% CI：1. 01- 1.07） ,P=0. 036]. There was no relationship between the volume of transfused RBC or platelets and the infection. Conclusions Transfusion of RBC stored for more than 14 days may be a risk factor for bacterial infection in trauma patients.