摘要
寻找理想的骨修复材料一直是骨组织工程领域的研究热点之一。本文对近5年来骨修复复合材料及其相关问题的研究进展进行综述。首先简述了骨修复复合材料的研究现状,其中包括纳米复合材料、负载活性因子的复合材料、引入基因工程的复合材料、磁性复合材料。然后对骨组织工程材料的血管化问题进行了较为深入的探讨。最后指出了目前骨修复复合材料存在的问题,并对其进行了前景展望。
To explore ideal materials for bone repair is one of the hot topics in the field of bone tissue engineering. In this paper, research progress on bone regeneration composite materials and related issues in the last five years were reviewed. We described the present research status of bone repair composite materials including nanocomposites, composite materials loaded with active factors, composite materials introduced genetic engineering, magnetic composite materials. Discussion in - depth for vascularization of bone tissue engineering materials was also given in the article. Meanwhile, problems existing in bone regeneration composites were pointed out while its prospect was also proposed.
出处
《中国生物医学工程学报》
CAS
CSCD
北大核心
2012年第5期755-761,共7页
Chinese Journal of Biomedical Engineering
基金
国家重大科学研究计划项目(2012CB933603)
浙江省新苗人才计划项目(2012R413046)
深圳市科技计划项目(JC200903170498A)
关键词
纳米复合材料
基因工程
生长因子
磁性粒子
血管化
nanocomposites
genetic engineering
growth factors
magnetic particles
vascularization
