中西医结合治疗惊恐障碍临床研究

Clinical Study on Panic Disorder Treated by the Integration of Chinese Medicine and Western Medicine

目的:探讨中西医结合治疗惊恐障碍的临床疗效。方法:将64例惊恐障碍患者随机分为观察组和对照组,每组各32例。对照组给予坦度螺酮胶囊治疗,观察组在对照组的基础上联合安神定志丸合朱砂安神丸治疗,两组疗程均为6周,于治疗前后采用HAMA、CGI和TESS评价临床疗效和不良反应。结果:观察组治疗前后HAMA评分比较,差异有统计学意义(P<0.01),与对照组比较,差异有统计学意义(P<0.05),两组比较,观察组HAMA评分下降更为明显,差异有统计学意义(P<0.05);两组CGI评分与治疗前比较,均有统计学意义(P<0.05),治疗6周后观察组CGI评分下降明显,两组比较,差异有统计学意义(P<0.05);两组不良反应比较,观察组与对照组比较,差异有统计学意义(P<0.05)。结论:中西医结合治疗惊恐障碍疗效显著,不良反应少。

Objective：To explore the clinical effects of the integration of Chinese medicine and Western medicine in treating panic disorder.Methods：64 cases of patients with panic disorder were randomly divided into the observation group and the control group witn each of 32 cases.The control group was given tandospirone capsule.Based on the control group,the observation group was combined with Anshen Dingzhi Wan and Cinnabaris Pill for Tranquilization.6 weeks were one course of treatment in the two groups,and clinical curative effects and adverse reaction were evaluated by HAMA score,CGI score and TESS score before and after treatment.Results：HAMA score had extremly difference in the observation group before and after treatment（P0.01）,significant difference in the control group（P0.05）,and HAMA score in the observation group decreased more obviously than the control group,and comparison between the two groups showed that the difference was significant（P0.05）;CGI score compared with before treatment significantly difference in the two groups（P0.05）,and 6 weeks after treatment CGI score in the observation group dropped apparently,which had significant differences between the two groups（P0.05）.Adverse reaction in the observation group was slighter than the control group,and the comparation between the two groups showed that differences had significance（P0.05）.Conclusion：The integration of traditional chinese medicine and western medicine has great effects on the treatment of panic disorder,and less adverse reaction.