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肠内免疫微生态营养对重症急性胰腺炎肠道通透性及临床预后的影响 被引量:4

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摘要 目的探讨肠内免疫微生态营养对重症急性胰腺炎(SAP)肠道通透性及临床预后的影响。方法将43例SAP患者随机分为肠内营养组(EN组)和肠内免疫微生态营养组(EIN组)。检测并比较两组治疗后1、3、5、7、14d外周血内毒素、D-乳酸、二胺氧化酶(DAO)的浓度及临床治疗效果。结果第1天EIN组内毒素、D-乳酸、DAO浓度与EN组比较差异无统计学意义(P〉0.05);EIN组从第5天起内毒素、D-乳酸、DAO浓度均较EN组明显下降(P〈0.01或P〈0.05);治疗结束后,APACHEⅡ评分、CT评分及感染发生率、手术率两组比较差异均有统计学意义(P〈0.05)。结论EIN能明显减少肠黏膜的通透性,达到保护肠黏膜屏障的作用并有助于改善SAP患者的临床预后。
出处 《中国实用医刊》 2012年第21期86-87,共2页 Chinese Journal of Practical Medicine
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