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青年乳腺癌中XIAP、Smac、Caspase-3的表达及其与HER2的相关性研究 被引量：2

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摘要 乳腺癌是女性最常见的恶性肿瘤之一。一般认为35岁以下青年乳腺癌患者在生物学行为及预后方面不同于其他年龄段患者，因此将之定义为青年乳腺癌。作者对本院近年来收治的35岁以下乳腺癌病例进行回顾性分析，
作者 刘志英 肖刚 刘铁菊
机构地区 河北省唐山市妇幼保健院普外科 天津医科大学病理教研室
出处 《河北医科大学学报》 CAS 2012年第10期1214-1216,共3页 Journal of Hebei Medical University
关键词 乳腺肿瘤 诊断 免疫组织化学
分类号 R737.9 [医药卫生—肿瘤]
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参考文献5

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  • 2COLONNA M, DELAFOSSE P, UHRY Z, et al. Is breast cancer incidence increasing among young women? An analysis of the trend in France for the period 1983 - 2002 [ J]. Breast ,2008,17 ( 3 ) : 289 - 292.
  • 3WANG ZH, CHEN H, GUO HC, et al. Enhanced antitumor efficacy by the combination of emodin and gemcitabine against human pancreatic cancer cells via downregulation of the expression of XIAP in vitro and in vivo[ J ]. lnt J 0ncol,2011,39 (5) :1123 - 1131.
  • 4YANG D,ZHAO Y,LI AY ,et al. Smac -mimetic compound SM - 164 induces radiosensitization in breast cancer cells through activation of caspases and induction of apoptosis [ J ]. Breast Cancer Res Treat,2012,133 ( 1 ) : 189 - 199.
  • 5GONZ.~LEZ - L6PEZ M, WELSH K, FINLAY D, et al. Design, synthesis and evaluation of monovalent Smac mimetics that bind to the BIR2 domain of the anti - apoptotic protein XIAP [ J ]. Bioorg Med Chem Lett,2011,21 (14) :4332 -4336.

二级参考文献34

  • 1王中华,徐兵河.129例30岁以下女性乳腺癌的临床特点及预后分析[J].中华肿瘤杂志,2005,27(2):111-113. 被引量：40
  • 2张晨芳,康慧鑫,张宏,刘颖.青年乳腺癌97例临床特点及预后分析[J].实用医学杂志,2006,22(12):1426-1427. 被引量：8
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共引文献3

同被引文献18

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二级引证文献10

河北医科大学学报
2012年 第10期

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