老年肺癌患者医院感染及其危险因素分析

Healthcare-associated infection and risk factors in elderly lung cancer patients

目的探讨老年肺癌住院患者发生医院感染的情况及其危险因素。方法对某院肿瘤科2006年5月—2011年5月年龄≥60岁的肺癌住院患者病历资料进行分析。结果 324例老年肺癌患者发生医院感染63例,医院感染率为19.44%;医院感染病原菌以革兰阴性杆菌为主(37株,58.73%),其次为革兰阳性球菌(20株,31.75%),真菌占9.52%(6株);感染部位以呼吸道和口腔为主,构成比分别为47.62%(30例)、17.46%(11例)。单因素分析结果显示,TNM分期、侵入性操作、抗肿瘤治疗、吸烟、合并基础疾病是老年肺癌患者发生医院感染的危险因素(P<0.05)。结论老年肺癌患者医院感染率较高,应针对其危险因素重点防控。

ObjectiveTo explore healthcareassociated infection（HAI） and risk factors in elderly lung cancer patients.MethodsMedical data of lung cancer patients aged≥60 years in a tumor hospital between May 2006 and May 2011 were analyzed retrospectively.ResultsOf 324 patients,63 （19.44%） developed HAI,the major pathogens were gramnegative bacilli （37 isolates, 58.73%）, the next were grampositive cocci （20 isolates, 31.75%）, fungi accounted for 9.52% （6 isolates）; the main infection sites were respiratory tract and oral cavity,the constituent ratio was 47.62%（30 cases） and 17.46%（11 cases） retrospectively. Univariate analysis revealed that the stage of TNM, invasive operation, antitumor therapy, smoking and associated underlying diseases were related risk factors for HAI in elderly patients with lung cancer（P〈0.05）.ConclusionHAI in elderly lung cancer patients is high, prevention and control should be taken according to related risk factors.