小儿特发性血小板减少性紫癜临床疗效观察 (附83例分析)

Clinical effective observation of the children with ldiopathic thrombocytopnic purpura

本文通过对８３例特发性血小板减少性紫癜四种方案治疗，即静脉丙种球蛋白，常规剂量强的松口服，大剂量地塞米松及甲基强的松龙冲击治疗观察，经过比较分析，结果表明：四种方案均可在短期内控制出血症状。除常规剂量强的松口服治疗外，三种方案可短期提高血小板数。静脉两种球蛋白虽短期疗效高，由于价格昂贵，本文认为对重症病例可首选甲基强的松龙或地塞米松冲击，一般病例仍以常规口服强的松为最佳选择。合并自身免疫性溶血性贫血病人预后差。

Eighty three cases of idiopathic thrombocytopermic purpura were managed by four medicine therapies included intravenous immunoglobulin,injective Dexamethethasome,oral Methylprednisolone and oral Prednison. The result demonstrated that the symptoms could be control by every one of four medicines and the level of thrombocyte count in all groups increase in short term except only in group using routine dose of Prednison. The conclusion of this study suggested that the better choise medicines are methylprednisoelone or Dexamethasone in severe cases and the first choise medicine is Prednison in general cases. The curative effect of immunoglobulin was best one in all four groups but its cost was expensive.The response was poul in the cases of idiopatlie thrombocytopenic purpura associated autoimmune hemolytic anemia.